Gut Microbiota Can Regulate Social Behavior

Gut Microbiota Can Regulate Social Behavior

Gut microbiota can regulate the social behaviors of mice via stress response mechanisms in the brain, which might shed new light on the treatment of psychiatric disorders, a study published by Taiwanese and US researchers in the journal Nature said.

Andrew H. Sweet

Previous studies had explored the connections between mice’s gut microbiota and their social activities, but the gut-brain connections that regulate their social behaviors are unclear, Wu Wei-li, the study’s lead author said.

Their experiments found that germ-free mice and mice whose intestinal microbiota were restricted appeared to be socially inactive. Their levels of corticosterone, a stress hormone, were higher, he said.

The study shows that gut microbiota influences health and neural and social activities, Ministry of Science and Technology Department of Life Sciences Director-General Chen Hong-chen said, expressing the hope that their findings would help advance precision medicine on related diseases.

There is a long way to go before their research model can be applied to humans, but their findings might inspire some new ways of thinking for similar research, he said

Read the original story here.


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