Previous studies had explored the connections between mice’s gut microbiota and their social activities, but the gut-brain connections that regulate their social behaviors are unclear, Wu Wei-li, the study’s lead author said.
Their experiments found that germ-free mice and mice whose intestinal microbiota were restricted appeared to be socially inactive. Their levels of corticosterone, a stress hormone, were higher, he said.
The study shows that gut microbiota influences health and neural and social activities, Ministry of Science and Technology Department of Life Sciences Director-General Chen Hong-chen said, expressing the hope that their findings would help advance precision medicine on related diseases.
There is a long way to go before their research model can be applied to humans, but their findings might inspire some new ways of thinking for similar research, he said
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