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How High-Sugar Diets Could Influence Pancreatic Cancer Risk

Scientists caution, however, that the evidence does not establish that sugar directly causes the disease.

Study Links Excess Insulin to Pancreatic Cancer Risk. Pic via(@ladbible)

Researchers are investigating whether persistently high insulin levels linked to diets high in sugar and ultra-processed foods could contribute to pancreatic cancer, particularly as cases rise among younger adults.

Scientists caution, however, that the evidence does not establish that sugar directly causes the disease.

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Research from the University of British Columbia found in mice that excessive insulin overstimulated pancreatic cells responsible for producing digestive enzymes, triggering inflammation and tissue damage.

In mice carrying KRAS mutations, which are present in more than 90 percent of human pancreatic cancers, this inflammatory environment helped precancerous cells develop.

Researchers are now examining whether excess insulin may also support tumour growth and whether changes in blood sugar and insulin could eventually serve as early warning signs.

Studies have also associated high consumption of ultra-processed foods with increased cancer risks. Experts stress that diet is only one potential factor and that further human research is needed to establish causation.

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