A King's College London study published in Nature suggests that obesity does not carry the same health risks for everyone and that BMI alone may be insufficient for accurate diagnosis.
Researchers analysed data from 844,108 adults across four countries, proposing a framework that combines BMI with waist circumference, body-fat measurements and indicators of organ dysfunction. It distinguishes between pre-clinical and clinical obesity to support more personalised treatment.
The findings indicate that BMI overestimated obesity in up to 3.1% of participants and underestimated it in up to 8.6%.
Senior author Professor Francesco Rubino said the framework aims to better match treatment intensity to individual health risks.
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— Reuters (@Reuters) November 11, 2026
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