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Study Links Low AST And ALT Levels To Early-Onset Colorectal Cancer

However, experts caution that the findings do not establish low enzyme levels as a cause or definitive predictor of cancer.

,   and  TIPP Staff
2 min read
Routine blood testing may hold hidden clues to colorectal cancer before age 45. Pic via(@CTVNews)

Low levels of two commonly measured liver enzymes may be associated with a higher likelihood of early-onset colorectal cancer in adults under 45, according to an Epic Research analysis published Wednesday.

Researchers analyzed health data from more than 11,000 U.S. adults aged 18 to 44. Those with AST levels below 14 units per liter had a 65% higher likelihood of being diagnosed with colorectal cancer, while those with similarly low ALT levels had a 68% higher likelihood.

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Colorectal cancer has increasingly affected younger adults in the United States, becoming the leading cause of cancer deaths among people under 50. Researchers are investigating whether metabolic and nutritional markers could help explain the trend.

However, experts caution that the findings do not establish low enzyme levels as a cause or definitive predictor of cancer.

Dr. Daniel Sussman of the University of Miami said the levels are generally considered normal and should not change current screening recommendations. Further research is needed to determine whether the findings apply more broadly.

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tippinsightsTIPP Staff

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