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Study Finds Most Urban Mice Are Developing Resistance To Rat Poison

Researchers from Rutgers University analyzed 147 house mice and 143 Norway rats, discovering that 84% of the mice carried at least one mutation in the Vkorc1 gene, while about 70% possessed mutations associated with resistance to widely used rodenticides.

Scientists Find Poison-Resistant Mutant Rats Spreading Across America’s Biggest Cities. Pic via (@gatewaypundit)

A new study published in Pest Management Science has found that urban house mice in the northeastern United States are increasingly developing genetic resistance to commonly used anticoagulant rodenticides, raising concerns about the long-term effectiveness of traditional pest control methods.

Researchers from Rutgers University analyzed 147 house mice and 143 Norway rats, discovering that 84% of the mice carried at least one mutation in the Vkorc1 gene, while about 70% possessed mutations associated with resistance to widely used rodenticides.

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According to entomologist Changlu Wang, repeated exposure to these chemicals over many years has driven the evolution of mice capable of surviving treatments that once proved effective.

The findings suggest that continued reliance on the same class of poisons could make rodent control increasingly difficult in urban environments.

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Researchers recommend rotating different types of rodenticides and combining chemical treatments with non-chemical strategies such as improved sanitation, exclusion measures and trapping.

Scientists also warned that increasing poison doses to overcome resistance could heighten risks to non-target wildlife and household pets, underscoring the need for more sustainable and integrated pest management practices.

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